Studies on Pseudorabies (infectious Bulbar Paralysis, Mad Itch) I . Histology of the Disease, with a Note on the Symptomatolooy

Pseudorabies has now been reported as occurring in Hungary (Aujeszky, 1902, and many others), Brazil (Carini and Maciel, 1912), United States (Shope, 1931, 1932), Denmark (Bang, 1932) and Holland (Burggraaf and Lourens, 1932). Although in this disease nervous symptoms are prominent, usually no lesions other than vascular congestion have been found in the nervous system. F#ger (1932) found hemorrhages and less often perivascular infiltration in cattle, but not in cats or rabbits. Among others, Bertarelli and MeUi (1913), Sangiorgi (1914) and F~lger have failed to detect cellular inclusions. In rabbits and guinea pigs, the extraordinarily rapid course of the malady, measured in hours, presumably allows little time for the development of gross pathological changes. Nevertheless characteristic lesions, identical whether the Aujeszky virus or Shope's Iowa strain ("mad itch") is employed, are usually present. In the following pages a description of these lesions is given.